本科和博士毕业于华中师范大学化学学院,获华中师范大学优秀博士论文;2011年-2014年在好意思国马里兰大学从事博士后相干;2014年加入西北大学化学与材料科学学院,任教学、博导。零丁责任时辰,先后荣获陕西省后生百东说念主方案、Thieme Chemistry Journals Award、栽种部霍英东后生教化基金、陕西省了得后生科学基金、国度当然科学基金委优秀后生科学基金;主握包括国度当然科学基金面上神志(4项)、陕西省当然科学基金面上神志(1项)和陕西省栽种厅要点科研方案(1项)等科研神志。主要围绕基于大环分子体系的仿生超分子化学规模开展相干责任,发展了在生物兼容环境中仿生超分子体系的构建偏执在生物分子的仿生识别活动、手性传递与放大机制以及光催化振荡与光能源调整等方面的附近;迄今以第一或通信作家发表J. Am. Chem. Soc., Angew. Chem. Int. Ed., CCS Chem.等期刊论文五十余篇;相关相干服从获陕西高等学校科学技能相干优秀服从一等奖(排行第一)和陕西省当然科学一等奖(排行第三)。 学习和责任阅历: 2014年-今:教学,博导,西北大学,化学与材料科学学院。 2017年-2018年:国度公派考核学者,好意思国犹他大学,化学系,融合导师:Peter Stang教学。 ai 萝莉2011年-2014年:博士后,好意思国马里兰大学,化学与生亏空学系,融合导师:Lyle Isaacs教学。 2006年-2011年:理学博士(有机化学),华中师范大学,化学学院,导师:吴释怀教学。 2002年-2006年:理学学士(附近化学),华中师范大学,化学学院。
基金神志: 国度当然科学基金委优秀后生科学基金 陕西省了得后生科学基金 栽种部霍英东高校后生教化基金 陕西省百东说念主方案(后生神志) 荣誉奖项: 陕西省优秀博士学位论文指挥教化(李亚雯) 宇宙超分子化学学术究诘会学术新星奖(宇宙大环化学暨超分子化学学术究诘会学术委员会和Angewandte Chemie编委会) 大环芳烃超分子化学学术新星奖(2020年度,第十届大环芳烃超分子化学学术研究会) 陕西省化学优秀后生奖(陕西省化学会) 西北大学2022年度科研奖(团队奖) 陕西高等学校科学技能相干优秀服从一等奖(排行第一) 陕西省当然科学一等奖(排行第三) 西北大学2021年度科研奖(个东说念主奖) 西北大学优秀博士学位论文指挥教化(李亚雯) 西北大学优秀硕士学位论文指挥教化(段红红) 西北大学2019-2020教学年度优秀教化 Thieme Chemistry Journals Award 华中师范大学优秀博士论文 学术兼职: 中国化学会第三十一届理事会超分子化学专科委员会委员 中国化学会高档会员 中国感光学会后生理事会理事 Chinese Chemical Letter高档编委 Aggregate后生护士人编委 相干主见: 1、新颖水溶性阳离子型荧光大环分子的合成及生物分子识别相干; 2、基于大环分子识别的刺激反馈型超分子拼装体系的开荒与附近; 3、基于大环的超分子框架材料:构筑、性质相干以及功能的附近。 连年来,课题组针对面前生物分子识别准确性差、手性信息反馈缺失等难点和瓶颈问题,通过开发水溶性大环超分子东说念主工体系,系统开展了生物分子识别与手性反馈机制的新旨趣和新智力相干,提倡了自妥当手性识别与反馈的机理,完了了氨基酸、核苷、多肽、卵白质以及DNA等生物分子的接收性识别与手性信号反馈,为生物分子检测与监测机制相干开荒了一类东说念主工仿生识别的超分子体系。
毕业学生(服务或升学单元): 博士毕业生: 2019年:鱼洋(西安交通大学) 2021年:李亚雯(西安交通大学)、王聘聘(枣庄学院) 2022年:程琳(西北大学) 2023年:段红红(守秘单元) 硕士毕业生: 2017年:李杰 2018年:王聘聘(西北大学) 2019年:张蓓琳(西北工业大学) 2020年:李晨阳(陕西能源工作技能学院)、段红红(西北大学) 2021年:年浩(南边科技大学)、张海洋(陕西隆基乐叶光伏科技有限公司)、秦春艳(山西稷王中学) 2022年:段燕娟(天津凯莱英医药)、王玲 2023年:田萍、马焕青 2024年:宋晓雯(山东鲁抗医药股份有限公司)、郭聪慧(威斯派尔半导体技能有限公司)、姚诺锦(比亚迪汽车有限公司) 本科毕业生: 2020年:敖宛彤(丹麦哥本哈根大学),金慧琳(比利时布鲁塞尔解放大学) 2024年:韩京娱(中国科学院理化技能相干所) 科研服从: 零丁责任(2014-今): 57. Li, J.; Li, R.; Liu, J.; Liu, J.-Q.;* Xu, J.; Zhou, X.; Zhang, Y.; Wang, K.; Lei, L.; Xie, G.; Wang, F.; Yang, Y.;* Cao, L.*, A TOC- and Deposition-Free Electrochromic Window Driven by Redox Flow Battery. Chin. Chem. Lett. 2024, 35, 110355. https://www.sciencedirect.com/science/article/pii/S100184172400874X 56. Nian, H.; Wang, S.-M.; Wang, Y.-F.; Zheng, Y.-T.; Zheng, L.-S.; Wang, X.; Yang, L.-P.;* Jiang, W.;* Cao, L.,* Selective Recognition and Enrichment of C70 over C60 Using an Anthracene-Based Nanotube. Chem. 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Cheng, L.; Tian, P.; Li, Q.; Li, A.; Cao, L.* Stabilization and Multiple-Responsive Recognition of Natural Base Pairs in Water by a Cationic Cage. CCS Chem. 2022, 4, 2914-2920. https://www.chinesechemsoc.org/doi/10.31635/ccschem.021.202101584 42. Wang, P.; Liu, K.; Ma, H.; Nian, H.; Li, Y.; Li, Q.; Cheng, L.; Cao, L.* Synthesis and Aqueous Anion Recognition of Imidazolium-Based Nonacationic Cup. Chem. Commun. 2021, 57, 13377-13380. https://pubs.rsc.org/en/content/articlehtml/2021/CC/D1CC05603D 41. Nian, H.; Cheng, L.; Wang, L.; Zhang, H.; Wang, P.; Li, Y.; Cao, L.* Hierarchical Two-Level Supramolecular Chirality of an Achiral Anthracene-Based Tetracationic Nanotube in Water. Angew. Chem. Int. Ed. 2021, 60, 15354-15358. https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/anie.202105593 40. Qin, C.; Li, Y.; Li, Q.; Yan, C.; Cao, L.* Aggregation-Induced Emission and Self-Assembly of Functional Tetraphenylethene-Based Tetracationic Dicyclophanes for Selective Detection of ATP in Water. Chin. Chem. Lett. 2021, 32, 3531-3534. https://www.sciencedirect.com/science/article/pii/S1001841721003107 39. Xu, W.; Duan, H.; Chang, X.; Wang, G.; Hu, D.; Wang, Z.; Cao, L.*; Fang, Y.* Polyanion and Anionic Surface Monitoring in Aqueous Medium Enabled by an Ionic Host-Guest Complex. Sensors and Actuators B: Chemical, 2021, 340, 129916. https://www.sciencedirect.com/science/article/pii/S0925400521004858 38. Duan, H.; Cao, F.; Hao, H.; Bian, H.; Cao, L.* Efficient Photoinduced Energy and Electron Transfers in a Tetraphenylethene-Based Octacationic Cage through Host-Guest Complexation. ACS Appl. Mater. & Interfaces 2021, 13, 16837-16845. https://pubs.acs.org/doi/10.1021/acsami.1c01867 37. Zhang, H.; Cheng, L.; Nian, H.; Du, J.; Chen, T.; Cao, L.* Adaptive Chirality of Achiral Tetraphenylethene-Based Tetracationic Cyclophanes with Dual Responses of Fluorescence and Circular Dichroism in Water. Chem. Commun. 2021, 57, 3135-3138. https://doi.org/10.1039/d1cc00303h 36. 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Wang, P.; Miao, X.; Meng, Y.; Wang, Q.; Wang, J.*; Duan, H.; Li, Y.; Li, C.; Liu, J.; Cao, L.* Tetraphenylethene-Based Supramolecular Coordination Frameworks with Aggregation-Induced Emission for Artificial Light-Harvesting System. ACS Appl. Mater. & Interfaces 2020, 12, 22630-22639. https://pubs.acs.org/doi/pdf/10.1021/acsami.0c04917 32. Li, Y.; Qin, C.; Li, Q.; Wang, P.; Miao, X.; Jin, H.; Ao, W.; Cao, L.* Supramolecular Organic Frameworks with Controllable Shape and Aggregation-Induced Emission for Tunable Luminescent Materials Through Aqueous Host-Guest Complexation. Adv. Opt. Mater. 2020, 1902154. https://onlinelibrary.wiley.com/doi/abs/10.1002/adom.201902154 31. Nian, H.; Li, A.; Li, Y.; Cheng, L.; Wang, L.; Xu, W.; Cao, L.* Tetraphenylethene-Based Tetracationic Dicyclophanes: Synthesis, Mechanochromic Luminescence, and Photochemical Reaction. Chem. Commun. 2020, 56, 3195-3198. https://doi.org/10.1039/d0cc00860e 30. Li, C.; Nian, H.; Dong, Y.*; Li, Y,; Zhang, B.; Cao, L.* Tetraphenylethene-Based Platinum(II) Bis-Triangular Dicycles with Tunable Emissions. Inorg. Chem. 2020, 59, 5713-5720. https://pubs.acs.org/doi/abs/10.1021/acs.inorgchem.0c00505 29. Li, C.; Zhang, B.; Dong, Y.*; Li, Y.; Wang, P.; Yu, Y.; Cheng, L.; Cao, L.* A Tetraphenylethene-Based Pd2L4 Metallacage with Aggregation-Induced Emission and Stimuli-Responsive Behavior. Dalton Trans. 2020, 49, 8051-8055. https://pubs.rsc.org/en/content/articlelanding/2020/DT/D0DT00469C#!divAbstract 28. Li, Y.; Dong, Y.; Cheng, L.; Qin, C.; Nian, H.; Zhang, H.; Yu, Y.; Cao, L.* Aggregation-Induced Emission and Light-Harvesting Function of Tetraphenylethene-Based Tetracationic Dicyclophane. J. Am. Chem. Soc. 2019, 141, 8412-8415 https://doi.org/10.1021/jacs.9b02617 27. Cao, L.*; Wang, P.; Miao, X.; Duan, H.; Wang, H.; Dong, Y.; Ma, R.; Zhang, B.; Wu, B.; Li, X.; Stang, P. J. 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19. Li, J.; Zhao, Y.; Dong, Y.; Yu, Y.; Cao, L.*; Wu, B. Supramolecular Organic Frameworks of Cucurbit[n]uril-Based [2]Pseudorotaxanes in the Crystalline State. CrystEngComm, 2016, 18, 7929-7933. 18. Dong, Y.; Cao, L.* Functionalization of Cucurbit[n]uril. Progress in Chemistry,(化学发扬) 2016, 28, 1039-1053. https://manu56.magtech.com.cn/progchem/CN/10.7536/PC160320 17. Li, J.; Yu, Y.; Luo, L.; Li, Y.; Wang, P.; Cao, L.*; Wu, B. Square [5]Molecular Necklace Formed from Cucurbit[8]uril and Carbazole Derivative. Tetrahedron Lett. 2016, 57, 2306-2310. https://www.sciencedirect.com/science/article/pii/S0040403916304105?via=ihub 16. Yu. Y.; Li, J.; Zhang, M.; Cao, L.*; Isaacs, L.* Hydrophobic Monofunctionalized Cucurbit[7]Uril Undergoes Self-Inclusion Complexation and Forms Vesicle-Type Assemblies. Chem. Commun. 2015, 51, 3762-3765. 博士后时辰责任(2011-2014): 15. Sigwalt, D.; Sekutor, M.; Cao, L.; Zavalij, P. Y.; Hostas, J.; Ajani, H.; Hobza, P.; Mlimaric-Majerski, K.*; Glaser, R.*; Isaacs, L.* Unraveling the Structure-Affinity Relationship between Cucurbit[n]urils (n = 7, 8) and Cationic Diamondoids. J. Am. Chem. Soc. 2017, 139, 3249-3258. (SCI, IF = 13, 一区top)
14. Cao, L.; Skalamera, D.; Zavalij, P. Y.; Hobza, P.*; Mlinarić-Majerski, K.*; Glaser R.*; Isaacs, L.* Influence of Hydrophobic Residues on the Binding of CB[7] toward Diammonium Ions of Common Ammonium•••ammonium Distance. Org. Biomol. Chem. 2015, 13, 6249-6254. (SCI, IF = 3.5)
13. Cao, L.; Šekutor, M.; Zavalij, P. Y.; Mlinarić-Majerski, K.*; Glaser R.*; Isaacs, L.* Cucurbit[7]uril.Guest Pair with an Attomolar Dissociation Constant. Angew. Chem., Int. Ed. 2014, 53, 988-993. (SCI, IF = 13.4, VIP paper and Poster of the frontispiece, 一区top)
12. Zhang, M.#; Cao, L.# (共同第一作家); Isaacs, L.* Cucurbit[6]Uril-Cucurbit[7]Uril Heterodimer Promotes Controlled Self-Assembly Of Supramolecular Networks And Supramolecular Micelles By Self-Sorting Of Amphiphilic Guests. Chem. Commun. 2014, 50, 14756-14759. (SCI, IF = 6.7, 一区)
11. Cao, L.; Isaacs,L.* Absolute and Relative Binding Affinity of Cucurbit[7]uril Towards A Series of Cationic Guests. Supramol. Chem. 2014, 26, 251-258. (SCI, IF = 2.1) 10. Cao, L.; Hettiarachchi, G.; Briken, V.*; Isaacs, L.* Cucurbit[7]uril Containers for Targeted Delivery of Oxaliplatin to Cancer Cells. Angew. Chem., Int. Ed. 2013, 52, 12033-12037. (SCI, IF = 13.4, 一区top)
9. Vinciguerra, B.#; Cao, L.# (共同第一作家); Cannon, J. R.; Zavalij, P. Y.; Fenselau, C.; Isaacs, L.* Synthesis and Self-Assembly Processes of Monofunctionalized Cucurbit[7]uril. J. Am. Chem. Soc. 2012, 134, 13133-12140. (SCI, IF = 11.4, 一区top) (Spotlights on Recent JACS Publications, J. Am. Chem. Soc. 2012, 134, 14265-14266.) 8. Cao, L.; Isaacs, L.* Daisy Chain Assembly Formed from a Cucurbit[6]uril Derivative. Org. Lett. 2012, 14, 3072-3075. (SCI, IF = 6.3, 一区) 7. Lucas, D.; Minami, T.; Iannuzzi, G.; Cao, L.; Wittenberg, J. B.; Anzenbacher, Jr. P.*; Isaacs, L.* Templated Synthesis of Glycoluril Hexamer and Monofunctionalized Cucurbit[6]uril Derivatives. J. Am. Chem. Soc. 2012, 134, 13133-12140. (SCI, IF = 11.4) 博士时辰责任(2006-2011): 6. Cao, L.; Wang, J. G.; Ding, J. Y.; Wu, A. X.*; Isaacs,L.* Reassembly Self-Sorting Triggered by Heterodimerization. Chem. Commun. 2011, 47, 8548-8550. (SCI, IF = 6.7, 一区)
5. Cao, L.; Meng, X. G.; Ding, J. Y.; Chen, Y. F.; Gao, M.; Wu, Y. D.; Li, Y. T.; Wu, A. X.*; Isaacs, L.* Nanotubular Non-Covalent Macrocycle Within Non-Covalent Macrocycle Assembly: (MeOH)(12) Encapsulated in Amolecular Clip Cyclododecamer. Chem. Commun. 2010, 46, 4508-4510. (SCI, IF = 6.7)
4. Cao, L.; Ding, J. Y.; Gao, M.; Wang, Z. H.; Li, J.; Wu, A. X.* Novel and Direct Transformation of Methyl Ketones or Carbinols to Primary Amides by Employing Aqueous Ammonia. Org. Lett. 2009, 11, 3810-3813. (SCI, IF = 6.3) (highlighted by Organic Chemistry Portal: -chemistry.org/abstracts/lit2/649.shtm; ChemInform, 2010, 41, DOI:10.1002/chin.201004082)
3. Cao, L.; Ding, J. Y.; Wang, J. G.; Chen, Y.; Gao, M.; Xue, W. J.; Wu, A. X.* Colorimetric Fluoride Sensor Based on a Bisthiourea Functionalized Molecular Clip. Synlett 2010, 2553-2556. (SCI, IF = 2.8)
2. Cao, L.; Ding, J. Y.; Yin, G. D.; Gao, M.; Li, Y. T.; Wu, A. X.* Thioglycoluril as a Novel Organocatalyst: Rapid and Efficient alpha-Monobromination of 1,3-Dicarbonyl Compounds. Synlett. 2009, 1445-1448. (SCI, IF = 2.8)
1. 曹利平; 高蒙; 李义涛; 丁娇阳; 吴彦东; 祝艳平; 佘能芳; 吴释怀* 二元拼装体集群时的高接收性杂化重组活动. 中国科学B辑: 化学, 2009, 39, 343-349. (国度中枢期刊)
参与编写专著 1. Cao, L.; Zhao, J.; Yang, D.; Yang, X.-J.; Wu, B.* Hydrogen Bonding-Driven Anion Recognition in Hydrogen Bonded Supramolecular Structures. Springer-Verlag Berlin Herdelberg, 2015, DOI:10.1007/978-3-662-45756-6_5.
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